Calnexin anticorps

N° du produit ABIN6251945

Cet anticorps anti-Calnexin est un anticorps Souris Monoclonal détectant Calnexin dans WB, IF, FACS et IHC (p). Adapté pour Humain.

Aperçu rapide pour Calnexin anticorps (ABIN6251945)

Antigène: Calnexin (CANX)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CANX-1541

Détail du produit anti-Calnexin anticorps

Specificité: Does not react with rat

Purification: Protein G affinity chromatography

Immunogène: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: WB: 0.5-1 μg/mL

Flow Cytometry: 0.5-1 μg/10^6 cells

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Titering of the Calnexin antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: Calnexin

Sujet: It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis